Targeted.

Solutions.

Publications

Novel.

Tsuji, S., Chen, X., Hancock, B., Hernandez, V., Visentin, B., Reil, K., Sabbadini, R., Giacalone, M., Godbey, WT.  Pre-clinical evaluation of VAX-IP, a novel bacterial minicell-based biopharmaceutical for nonmuscle invasive bladder cancer. (2016) Molecular Therapy - Oncolytics​, Vol. 3, 16004; doi:10.1038/mto.2016.4


​Tsuji, S., Nahli, I., Authement, N., Segall, A., Hernandez, V., Hancock, B., Giacalone, M., Maloy, S.  An efficient thermoinducible bacterial suicide system - Elimination of viable parental bacteria from minicells. (2010) BioProcess International, Vol. 8, No. 4, 28-40.


Giacalone M.J., Sabbadini, R.A., Zapata, J.A., Chu Y.L., Berkley, N.L., Salvato M.S., and McGuire, K. Immunization with non-replicating E. coli minicells delivering both protein antigen and DNA protects mice from lethal challenge with lymphocytic choriomeningitis virus. Vaccine,25;12 (2007), 2279-2287.


Giacalone, M. J., S. Pillai, A. L. Chambers, R. A. Sabbadini, K. McGuire. 2006. Antigen-specific antibody production generated by bacterial minicells. Vaccine, 24 (2006), 6009-6017


Giacalone, M. J., A. M. Gentile, B. T. Lovitt, M. W. Surber, R. A. Sabbadini. 2006. The use of bacterial minicells to transfer plasmid DNA to eukaryotic cells. Cellular Microbiology (2006), 8(10), 1624-1633. 

Giacalone, M. J., N. L. Berkley, B. T. Lovitt, A. M. Gentile, C. W. Gunderson and M. W. Surber.  Toxic protein expression in Escherichia coli using a rhamnose-based tightly regulated and tunable promoter system. Biotechniques, (2006) 40, 355-364.