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Technology Overview
Vaxiion's proprietary vaccine technology is capable of the simultaneous delivery of protein antigens and DNA to cells of the immune system that can also be engineered to target and deliver to specific cell and tissue types. Minicells are small, semi-spherical, bacterial nano-particles (shown budding off of the polar region of a parental E. coli cell expressing green flourescent protein). Minicells have all of the immunogenic components of bacteria but cannot divide and are non-infectious. Easily manipulated using standard genetic techniques, minicells serve as a smart vaccine delivery vehicle for viral, bacterial, and parasitic organisms as well as certain types of cancers. Currently, Vaxiion minicells are being developed as a multi-component Traveler's vaccine against enteric bacterial pathogens.
Vaxiion's proprietary minicell-producing E. coli strain co-producing GFP and minicells.